CAIRO – The US has called on Egypt's army to free deposed President Mohamed Morsi, amid ongoing protests on the first Friday of Ramadan.
The appeal echoed a similar call hours earlier from Germany.
The Islamist Mr Morsi, who was ousted last week after the army stepped in, has since been held at a "safe" but unspecified location.
Dozens of people have since died in clashes during major demonstrations by pro- and anti-Morsi protesters.
Mr Morsi's supporters gathered in their tens of thousands in the east of the capital, Cairo, on Friday – the first Friday of the fasting month of Ramadan – demanding his reinstatement.
American officials are struggling to articulate a policy on Egypt and their public statements seem driven mostly by fear of the reaction on the streets of Egypt.
When Mohammed Morsi was elected last year, there was relief in Washington. There were predictions of widespread violence if his opponent, Mubarak-era official Ahmad Shafiq, had been declared the victor.
Despite deep misgivings about Mr Morsi, the US tried to maintain a working relationship with him. Egypt's opposition accused the US of being in bed with the Muslim Brotherhood.
Since Mr Morsi was ousted, Washington has called for an end to arbitrary arrests but had avoided calling specifically for his release – for fear of provoking a backlash in Cairo by the anti-Morsi crowd.
When Germany said he should be freed from house arrest, the US was put on the spot. During the daily briefing, State Department Spokeswoman Jen Psaki was asked whether the US agreed with Germany. She had little choice but to answer that the US did agree.
Protesters against Mr Morsi, whose mass demonstrations led to his removal by the army last week, gathered in smaller numbers in Tahrir Square.
Mr Morsi's Muslim Brotherhood movement may have alienated many people while in office, but many Egyptians are also uneasy at the military's intervention in the country's politics, analysts say, and what is emerging is a battle for public opinion and the middle ground.
Washington had so far avoided calling in public for the release of Mohammed Morsi, only urging the Egyptian army to stop arbitrary arrests without specifically referring to the deposed president, says the BBC's Kim Ghattas in Washington.
But after Germany said Mr Morsi should be freed from house arrest, the US was put on the spot, adds our correspondent.
Earlier on Friday, Germany's foreign ministry had urged the Egyptian authorities to end restrictions on Mr Morsi and allow an international organisation, such as the Red Cross, access to him.
Asked if the US agreed that he should be released, state department spokeswoman Jen Psaki told reporters: "We do agree."
On Thursday, Washington had urged Egypt's leadership to stop the "arbitrary" arrests of Muslim Brotherhood members, warning against targeting any particular group.
However, White House spokesman Jay Carney said that the US administration did not believe it should immediately suspend aid to Egypt.
Washington is due to send four F-16 fighter jets to Egypt, but has not publicly confirmed that the delivery will go ahead.
The US says it is examining whether the military takeover constitutes a coup – US law prohibits the sending of aid to any country whose elected leader is deposed by a military coup.
UN chief Ban Ki-moon has warned against the exclusion of any party from the political process.